Food

CONTAMINATS AND ADDITIVES LABORATORY

The contaminants and additives division deals daily with issues that arise in a society careful to health and the protection of the environment, for this reason it is constantly involved to receive with authoritativeness and rapidity the requirements of the costumers.

The staff of the Contaminants and Additives division of Chelab, is composed by 20 highly specialized analysts,15 of them are graduated (in chemistry and industrial chemistry, chemistry and pharmaceutical chemistry) and 5 are qualified chemists.
The analyzed matrices are different and include: cereals and by-products, feed and feeding mixtures, vegetables and fruits, meat and meat giblets, biological liquids, marine and freshwater animals, eggs, apiculture products, milk and by-products. The same importance have also the liquid coming from leaching tests and environmental samples, for example the waters and the stack emissions.
The activity of this department can be divided into three principal categories:

• Residues of contaminants research
• Control of the quantity of added additives
• Allergens research

In all cases, the analysis consists of many steps: the extraction of active principle or the researched compound from the sample, one or more purifications of the raw extract and finally the quantitative and qualitative determination, using the cutting-edge equipment of the laboratory.

Among the most researched active principles, we can list, for example:

TOXINS
• Ochratoxin • Trichothecenes • Fumonisin • Ergosterol • Zearalenon • Aflatoxins B, G and M • Patulin
ANTIBIOTICS/CHEMOTHERAPEUTICS
• Amphenicols • Beta-lactams • Streptomycin • Bacitracin Zinc • Theophylline • Quinolones • Colistin • Abamectin • Ionophores • Sulfonamides • Macrolides	• Tetracyclines and metabolites • Aminoglycosides • Flavomycin • Metabolites of nitrofuran chemotherapeutics • Nitroimidazolic chemotherapeutics • Non Steroidal Anti-Inflammatory Drugs (NSAIDs) • Malachite Green and Leucomalachite • Benzimidazole Chemotherapeutics • Nicarbazine • Avilamycin • Tiamulin
CONTAMINANTS
• Acrylamide • PCB (polychlorobiphenyl) • Radioactivity • PAHs (Polycyclic Aromatic Hydrocarbons) • Phthalates • TDI (Toluene Diisocyanate) • Badge and Bfdge • 3 -chloro-1,2-propandiol(3-MCPD) • Erucamide and oleamide • Melamine • Nicotine • ITX • Pentachlorophenol • Tris (nonylphenyl)phosphite • Octadecyl Propionate • Esbo • Bisphenol A
ADDITIVES (in addition to the already mentioned antibiotics)
• Benzoic and Sorbic acids • Monoglycerides and diglycerides of fatty acids • BHA (Butylated Hydroxyanisole) • BHT (Butylated Hydroxytoluene) • Rodenticides • Pimaricine • Parabens • Vitamin D3 and D2 • Alkyl Gallates • EDTA • IMU (imidazolidinylurea)
HORMONES
• Progestin-based • Androgens • Stilbenics • Cortisonics • Thyroid hormones
BETA AGONISTS

The laboratory is strongly committed to the development of new analytical methodologies and to the continuous improvement of the existing ones, because there are only few official methods for the detection of contaminants and additives in alimentary products. For this aim, this department makes a use of a well furnished library with the most prestigious and up-to-date international publications.The testing methods are anyway accurately validated and many of them are SINAL accredited.

Instruments contaminants and additives laboratory

3 Gas Chromatographs equipped with mass detector, mass/mass and ECD

	2 UPLC- double quadrupole
	1 UPCL triple quadrupole
	2 system LC/MDS equipped with source ESI and APCI
	3 system LC/MSD Ion trap
	1 Micro plate reader for Elisa kit
	4 HPLC equipped with Diode-Array detectors and fluorimeter
	1 Gamma spectrometer with germanium detector - HPGe (High Purity Ge)
	1 Gamma spectrometer with sodium iodide detector (NaI) crystal activated with thallium (NaJ(Tl))